Mind uploading may potentially be accomplished by either of two methods: copy-and-upload or copy-and-delete by gradual replacement of neurons (which can be considered as a gradual destructive uploading), until the original organic brain no longer exists and a computer program emulating the brain takes control over the body. According to supporters, many of the tools and ideas needed to achieve mind uploading already exist or are currently under active development however, they will admit that others are, as yet, very speculative, but say they are still in the realm of engineering possibility. Substantial mainstream research in related areas is being conducted in neuroscience and computer science, including animal brain mapping and simulation, development of faster supercomputers, virtual reality, brain–computer interfaces, connectomics, and information extraction from dynamically functioning brains.

The computer would then run a simulation of the brain's information processing, such that it would respond in essentially the same way as the original brain and experience having a sentient conscious mind.

Mind uploading is a speculative process of whole brain emulation in which a brain scan is used to completely emulate the mental state of the individual in a digital computer.

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